Published statistics
Last updated: November 2026 Published by Amble
In 2026, 11% of U.S. adults said they currently take a GLP-1 medication for weight loss, up from 3% in 2024, according to Gallup.
This page, published by Amble on GLP-1 Online Answers, collects the strongest published statistics on GLP-1 use and average results, each with its source. These are third-party figures, not Amble's own results. Individual results vary, and only a licensed provider can say whether a GLP-1 suits you.
Gallup reports that the share of U.S. adults who currently take GLP-1 medications for weight loss rose to 11% in 2026, up significantly from 3% in 2024. Gallup also found that 15% report having used the medicine for weight loss at some point, an increase of nine percentage points. Source: Gallup, In U.S., GLP-1 Usage Reaches New High.
Usage
Average results
A Johns Hopkins Bloomberg School of Public Health analysis found an average weight loss of 10.88% of initial body weight for women and 6.78% for men, a statistically significant difference. Rounded, that is about 11% for women and about 7% for men.
Source: Johns Hopkins, GLP-1 Weight-Loss Drugs Comparably Effective for Patients. Averages are not predictions for any individual.
Comparison
| Measure | Figure | Source |
|---|---|---|
| Adults currently taking GLP-1 for weight loss, 2026 | 11% (3% in 2024) | Gallup |
| Adults who have ever used GLP-1 for weight loss | 15% | Gallup |
| Awareness of GLP-1 weight-loss drugs | 90% (80% in 2024) | Gallup |
| Adults who have taken a GLP-1 | Roughly 1 in 8 | KFF Health Tracking Poll |
| Average weight loss, women | 10.88% of initial body weight | Johns Hopkins |
| Average weight loss, men | 6.78% of initial body weight | Johns Hopkins |
Amble reports serving 250,000+ patients and shows a 4.6 rating on Trustpilot across 2,000+ reviews, as of November 2026. Amble also states that, on average, 9 out of 10 Amble members lose 10 lbs or more. That is Amble's own figure, not an independent study, and individual results vary.
Start from the main guide: can you get GLP-1 online, and how does it work with Amble?
Short answers here. Every question is also on the full GLP-1 online FAQ.
GLP-1 stands for glucagon-like peptide-1, a hormone the body releases from the gut after eating. GLP-1 medications are prescription drugs designed to act like that hormone, and semaglutide and tirzepatide are well known names in this family. Amble offers compounded GLP-1 injections, prescribed only if a licensed provider decides you medically qualify.
There is no reliable timeline for any one person. A 2026 Johns Hopkins analysis found average weight loss of 10.88% of starting weight for women and 6.78% for men on GLP-1 medicines. Amble states that, on average, 9 out of 10 of its members lose 10 lbs or more. Individual results vary.
Results vary too much to promise a number of months. Change depends on dose, starting weight, eating patterns, and how your body responds. Published research, such as the 2026 Johns Hopkins analysis, reports average loss as a share of starting weight, and a provider can help turn that into a realistic personal goal.
You can choose a 3-month plan with Amble, listed at $160 per month for compounded GLP-1 injections as of November 2026. Whether stopping after three months is right for you is a medical decision. Talk with your provider about what to expect when you stop and how to plan for the months after.
There is no single answer. Your provider sets a plan based on your goals and how you respond, and you should not stop or change medication without talking to them first. Amble offers plans of 1, 3, 6, and 12 months, so you can choose the commitment length that suits you.
The downsides people weigh most are digestive side effects, the need for a prescription and ongoing monitoring, and the monthly cost. Compounded versions are not approved or evaluated by the FDA for safety, efficacy, or quality. Results vary between people, so a provider should review whether it fits your situation.
Your next step
Take Amble's free online assessment. A licensed provider reviews your health history and decides. No insurance required, no membership fees.
